Introduction The eye and its adnexal tissues are frequently affected in the course of leprosy. In many cases, the involvement is the result of invasion of the eye by the bacilli but in others the ocular lesion is the result of sequelae of infection of adjacent tissues or nerves. However, since leprosy usually is a chronic low-grade infection beginning in childhood and persisting through an only moderately shortened average life span, a certain number of patients are affected by diseases of the eye found in nonleprous patients. In addition, in many countries in which leprosy is prevalent, superimposed and secondary infections or infestations play a considerable role in the development of ocular lesions. The present paper is the first of a series of reports on a study made to correlate the clinical and pathologic findings in a group of patients, most of whom show a pure leprotic infection. Corneal Lesions