Opiates and Human Chromosome Alterations
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in International Journal of the Addictions
- Vol. 15 (2), 155-163
- https://doi.org/10.3109/10826088009040004
Abstract
Cytogenetic studies on cultured lymphocytes showed an increase in the frequency of chromosome breaks in heroin addicts (2.6%) compared to controls (0.4%). Within the 1st yr, patients on methadone maintenance had a decline in the frequency of chromosome damage. Investigation of former addicts who were not exposed to heroin for over 1 yr revealed a remarkably low frequency of cells with damage for both methadone users (0.8%) and for those not using methadone (0.6%). Long-term treatment programs reverse the cytogenetic alterations found in heroin users.This publication has 10 references indexed in Scilit:
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