Antigens of Human Seminal Plasma.

Abstract

Human semen, seminal plasma and spermatozoa contain a powerful antigen, which shows a high degree of specificity as compared with human serum and organ extracts. A distinction between seminal plasma and spermatozoa could not be obtained with immunological techniques. Evidence is presented that the dominant antigenic material is derived from the fluid constituents of the semen rather than from the spermatozoa. Human spermagglutinating sera do not give complement fixation with seminal plasma or spermatozoa, but they produce a zone of precipitation with seminal plasma in the agar diffusion test.