EFFECTS OF NEOMYCIN AND PENICILLIN ADMINISTRATION ON MUCOSAL PROLIFERATION OF THE MOUSE SMALL INTESTINE
Open Access
- 1 May 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 129 (5), 1063-1078
- https://doi.org/10.1084/jem.129.5.1063
Abstract
The effects of an oral neomycin and penicillin regimen on intestinal bacteriology and on morphology and function of the small intestine of mice were investigated. Quantitative and qualitative stool cultures on selective media of the treated animals revealed only growth of yeast organisms. The treated animals developed enlargement of the ceca with fluid contents and watery stools, resembling characteristics of germfree animals.Keywords
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