The Effect of Purified Lipopolysaccharide on the Bactericidal Reaction of Human Serum Complement
- 1 March 1980
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 117 (1), 65-72
- https://doi.org/10.1099/00221287-117-1-65
Abstract
Escherichia coli ML308 225 was killed and lysed by human serum. Bacterial sensitivity to serum was maximal for organisms in the early-exponential phase of batch culture and declined as growth proceeded. Bacterial killing was dependent upon the complete complement sequence and the subsequent action of serum lysozyme caused bacteriolysis. Purified lipopolysaccharide from this organism bound to serum-sensitive bacteria and inhibited the bactericidal reaction.This publication has 3 references indexed in Scilit:
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- Kinetics of the Transformation of Gram-Negative Rods to Spheroplasts and Ghosts by SerumThe Journal of Immunology, 1966
- Kinetics of the Bactericidal Action of Normal Serum on Gram-Negative BacteriaThe Journal of Immunology, 1965