THE EFFECT OF THE THYROTROPIC HORMONE ON AUTO- AND HOMEOTRANSPLANTS OF THE THYROID AND ITS BEARING ON THE QUESTION OF SECRETORY NERVES

Abstract

Evidence is presented showing that the thyrotropic hormone stimulates autothyroid transplants in immature guinea pigs to the same degree in the same time as the non-transplanted thyroid. This reaction is brought about by stimulation of the thyroid cells through the blood stream. It is grossly manifest in 2-3 days and cannot be associated directly with a nervous mechanism. This interpretation is even more strongly supported by the fact that homeotransplants of the thyroid are stimulated by the thyrotropic hormone (probably as intensely as autotransplants) during their survival period, even though the usual destructive processes of an immunological nature set in about the 8th day.