Responses of human peripheral lymphocytes to soluble and insoluble antigens of Candida albicans

Abstract

SUMMARY. Responses of peripheral lymphocytes from the blood of 20 healthy volunteers were determined in vitro by measurement of tritiated thymidine uptake in the presence of six different antigens prepared from Candida albicans. Crude antigens (disintegrated cells, culture filtrate) produced greater lymphoblast reactivity than purified preparations (cytoplasmic proteins, cell-wall mannan).