Abstract
In a series of 54 healthy men and 84 healthy women, plasma and leukocyte vitamin C concentration of the men was found to be significantly lower than that of the women. For nonsmokers, there was a significant decline in the plasma vitamin C concentration with increasing age in the men and the women but the leukocyte concentration did not change with age. The cigarette smoking habit was found to lower significantly both the plasma and the leukocyte vitamin C concentration.