The resolution of inflammation
Top Cited Papers
- 30 November 2012
- journal article
- viewpoint
- Published by Springer Nature in Nature Reviews Immunology
- Vol. 13 (1), 59-66
- https://doi.org/10.1038/nri3362
Abstract
In 2012, Nature Reviews Immunology organized a conference that brought together scientists and clinicians from both academia and industry to discuss one of the most pressing questions in medicine — how do we turn off rampant, undesirable inflammation? There is a growing appreciation that, similarly to the initiation of inflammation, the resolution of inflammation is an intricate and active process. Can we therefore harness the mediators involved in resolution responses to treat patients with chronic inflammatory or autoimmune diseases? Here, we ask five of the speakers from the conference to share their thoughts on this emerging field.Keywords
This publication has 62 references indexed in Scilit:
- Infection regulates pro-resolving mediators that lower antibiotic requirementsNature, 2012
- Resolution of inflammation by N‐arachidonoylglycineJournal of Cellular Biochemistry, 2011
- Chemical Mediators of Inflammation and Resolution in Post-Operative Abdominal Aortic Aneurysm PatientsInflammation, 2011
- Metabolic oxidation regulates embryonic stem cell differentiationNature Chemical Biology, 2010
- Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsisNature, 2009
- A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditisThe Journal of Pathology, 2008
- Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammationNature Immunology, 2008
- Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infectionThe Journal of Experimental Medicine, 2008
- Resolution of in flammation: state of the art, definitions and termsThe FASEB Journal, 2007
- Resolution of inflammation: the beginning programs the endNature Immunology, 2005