Abstract
Many cases of liver damage occur without jaundice but with ascites, pruritus, hematemesis, melano-derma, or enlargement of liver or spleen. The cholecysto-graphic examination, the bromsulphalein test, and the van den Bergh reaction are the most valuable tests to perform. 4 types of cases are cited: atrophy associated with disease of the gall bladder and biliary tract; atrophy associated with syphilis or with its treatment; atrophy of exogenous toxic origin; atrophy unassociated with other diseases. Liver damage is suspected when the patient complains of recurring mild indigestion, anorexia, nausea, constipation, headaches, weakness and loss of wt.

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