Origin ofNoise in Membrane Channel Currents
- 20 September 2002
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 89 (15), 158101
- https://doi.org/10.1103/physrevlett.89.158101
Abstract
The transport characteristics of nanofabricated synthetic pores of similar dimensions to those of biological channels is reported. By comparison of the ion current through single synthetic and biological channels we show that the noise indeed originates from the channel’s opening-closing process. Strong evidence has been provided that the latter is related to the underlying motions of channel wall constituents.
Keywords
This publication has 13 references indexed in Scilit:
- Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolutionNature, 2001
- Diode-like single-ion track membrane prepared by electro-stoppingNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2001
- Examining Noise Sources at the Single-Molecule Level:Noise of an Open Maltoporin ChannelPhysical Review Letters, 2000
- Non-Markovian character of ionic current fluctuations in membrane channelsPhysical Review E, 1998
- Elucidation of the Chain Conformation in a Glassy Polyester, PET, by Two-Dimensional NMRScience, 1998
- The Structure of the Potassium Channel: Molecular Basis of K + Conduction and SelectivityScience, 1998
- Structural Conservation in Prokaryotic and Eukaryotic Potassium ChannelsScience, 1998
- Pore geometry of etched ion tracks in polyimideNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1996
- Electrolyte transport in charged single ion track capillariesNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1995
- noise and other slow, nonexponential kinetics in condensed matterReviews of Modern Physics, 1988