Regulation of FOXO protein stability via ubiquitination and proteasome degradation
- 1 November 2011
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Vol. 1813 (11), 1961-1964
- https://doi.org/10.1016/j.bbamcr.2011.01.007
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (CA134514, CA130908)
- Department of Defense (W81XWH-07-1-0137, W81XWH-09-1-622)
- National Cancer Institute (CA125747, CA121277, CA091956)
- The T.J. Martell Foundation
This publication has 28 references indexed in Scilit:
- Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localizationCell Cycle, 2010
- SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma PrognosisGastroenterology, 2009
- Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKBNature Cell Biology, 2009
- Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destructionNature Cell Biology, 2009
- Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiencyCancer Cell, 2004
- Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradationProceedings of the National Academy of Sciences, 2003
- Akt Activation Promotes Degradation of Tuberin and FOXO3a via the ProteasomeJournal of Biological Chemistry, 2003
- 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportThe Journal of cell biology, 2002
- PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27KIP1 through the ubiquitin E3 ligase SCFSKP2Current Biology, 2001
- Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTENMolecular and Cellular Biology, 2000