The Effect of Machine Speed on the Consolidation of Four Directly Compressible Tablet Diluents
- 1 March 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 41 (3), 149-151
- https://doi.org/10.1111/j.2042-7158.1989.tb06418.x
Abstract
The reduction in porosity of a powder bed on compression was found to be a function of the velocity of the punch of the press. Substances which consolidated principally by fragmentation showed relatively little velocity dependence. However, the more important deformation was in a powder’s consolidation mechanism, the greater the dependence on punch velocity and hence tablet press speed.This publication has 7 references indexed in Scilit:
- Time-dependent factors involved in powder compression and tablet manufactureInternational Journal of Pharmaceutics, 1989
- Studies on tableting properties of lactoseInternational Journal of Clinical Pharmacy, 1985
- The effect of punch velocity on the compaction of a variety of materialsJournal of Pharmacy and Pharmacology, 1985
- A proposed consolidation parameter for powdersJournal of Pharmacy and Pharmacology, 1983
- Time-dependent deformation of some direct compression excipientsJournal of Pharmacy and Pharmacology, 1978
- Plastic Flow during Compression of Directly Compressible Fillers and Its Effect on Tablet StrengthJournal of Pharmaceutical Sciences, 1977
- Effect of Particle Size and Speed of Compaction on Density Changes in Tablets of Crystalline and Spray-Dried LactoseJournal of Pharmaceutical Sciences, 1971