Effect of Pituitrin in Reducing Portal Pressure in the Human Being

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Abstract
THE observation that Pituitrin has a depressor effect on portal-vein pressure in the laboratory animal is not new and has been verified by a number of workers.1 Repetition of these studies in experimental preparations using intrasplenic-pulp pressure as a mirror of portal pressure2 has confirmed the depressor effect of Pituitrin on portal venous pressure both in the normotensive and in the portal-hypertensive animal. Application of the intrasplenic method3 , 4 and development of a new technic5 , 6 for instantaneous estimation of portal blood flow have enabled us to extend these studies to human subjects. Details of these technics are reported elsewhere, but the . . .