On the binding of iabelled saxitoxin to the squid giant axon
- 22 August 1984
- journal article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 222 (1227), 147-153
- https://doi.org/10.1098/rspb.1984.0055
Abstract
Measurement of the maximum saturable binding capacity for 3H-labelled saxitoxin in well cleaned giant axons from Loligo forbesi gave a value of 290 +/- 65 (s.e.m.) binding sites per square micrometre of membrane. In samples of the fin nerve the total saturable uptake was 12.4 +/- 2.4 fmol mg-1 wet mass, corresponding to 94 sites per square micrometre for fibres whose mean diameter after fixation and embedding was estimated as 16 micron.Keywords
This publication has 6 references indexed in Scilit:
- Sodium channels in the axolemma of unmyelinated axons: a new estimateBrain Research, 1984
- Binding of radioactively labeled saxitoxin to the squid giant axonThe Journal of Membrane Biology, 1979
- The binding of labelled saxitoxin to the sodium channels in normal and denervated mammalian muscle, and in amphibian muscle.The Journal of Physiology, 1977
- A new method for labelling saxitoxin and its binding to non‐myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.The Journal of Physiology, 1976
- The rate of action of tetrodotoxin on sodium conductance in the squid giant axonPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1975
- The binding of tritiated tetrodotoxin to squid giant axonsPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1975