Sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo
- 15 July 1982
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 206 (1), 177-179
- https://doi.org/10.1042/bj2060177
Abstract
The sensitivity of carnitine acyltransferase I (EC 2.3.1.21) activity to malonyl-CoA inhibition in rat liver mitochondria isolated from animals in various physiological states was quantitatively proportional to the hepatic malonyl-CoA concentration in vivo. It is suggested that this relationship between the two parameters could result in a potent amplification mechanism for the reciprocal regulation of fatty acid synthesis and oxidation.This publication has 11 references indexed in Scilit:
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