Microwave tomography of extremities: 1. Dedicated 2D system and physiological signatures
- 2 March 2011
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 56 (7), 2005-2017
- https://doi.org/10.1088/0031-9155/56/7/006
Abstract
Microwave tomography (MWT) is a novel imaging modality which might be applicable for non-invasive assessment of functional and pathological conditions of biological tissues. Imaging of the soft tissue of extremities is one of its potential applications. The feasibility of this technology for such applications was demonstrated earlier. This is the first of two companion papers focused on an application of MWT for imaging of the extremity's soft tissues. The goal of this study is to assess the technical performance of the developed 2D MWT system dedicated for imaging of functional and pathological conditions of the extremity's soft tissues. Specifically, the system's performance was tested by its ability to detect signals associated with physiological activity and soft tissue interventions (circulatory related changes, blood flow reduction and a simulated compartmental syndrome)--the so-called physiological signatures. The developed 2D MWT system dedicated to the imaging of animal extremities demonstrates good technical performance allowing for stable and predictable data acquisition with reasonable agreement between the experimentally measured electromagnetic (EM) field and the simulated EM field within a measurement domain. Using the system, we were able to obtain physiological signatures associated with systolic versus diastolic phases of circulation in an animal extremity, reperfusion versus occlusion phases of the blood supply to the animal's extremity and a compartment syndrome. The imaging results are presented and discussed in the second companion paper.Keywords
This publication has 29 references indexed in Scilit:
- Microwave tomography: review of the progress towards clinical applicationsPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2009
- A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeriesPhysics in Medicine & Biology, 2007
- A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeriesPhysics in Medicine & Biology, 2007
- Initial Clinical Experience with Microwave Breast Imaging in Women with Normal MammographyAcademic Radiology, 2007
- Three-dimensional microwave tomography: initial experimental imaging of animalsIEEE Transactions on Biomedical Engineering, 2002
- Microwave detection of breast cancerIEEE Transactions on Microwave Theory and Techniques, 2000
- Spatial resolution of microwave tomography for detection of myocardial ischemia and infarction-experimental study on two-dimensional modelsIEEE Transactions on Microwave Theory and Techniques, 2000
- Three-dimensional microwave tomography: experimental prototype of the system and vector Born reconstruction methodIEEE Transactions on Biomedical Engineering, 1999
- Microwave tomography: two-dimensional system for biological imagingIEEE Transactions on Biomedical Engineering, 1996
- Microwave imaging of tissue blood content changesJournal of Biomedical Engineering, 1991