Vitamin Studies in Middle-Aged and Old Individuals V. Hypovitaminemia B1 Effect of Thiamine Administration on Blood Thiamine Concentration and Clinical Signs and Symptoms

Abstract

In an investigation of 20 elderly patients with low blood thiamine values, treatment with 5 mg. of thiamine hydrochloride by mouth was followed by a beneficial effect on existing edema of the legs and tenderness of the calves. The thiamine treatment also resulted in the attainment of normal thiamine blood values.