Some Extensions of von Braun (BrCN) Reaction on Organic Bases

Abstract
Von Braun Cyanogen Bromide Reaction Some extensions of von Braun cyanogen bromide reaction have been undertaken on conessine, isoconessine and two simpler bases, dimethyl a-naphthyl amine and diethyl amine. The monocyanamides of conessine and isoconessine yielded acid amides, amino-derivatives (diamines) and guanido derivatives on careful hydrolysis, reduction and treat-ment with ammonia, respectively. The simpler bases also formed the acid amides and dia-mines but failed to give the guanido derivatives under the conditions employed for conessine series. Diamines of all these bases yielded carbinol amines on reaction with nitrous acid.