RNA Sequences in Ribonucleoprotein Fragments of the Complex Formed from Ribosomal 23‐S RNA and Ribosomal Protein L24 of Escherichia coli

Abstract

Upon digestion of the complex formed from the 23-S rRNA and the 50-S ribosomal protein L24 of E. coli, 2 fragments resistant to RNase were recovered; these fragments contained RNA sections belonging to the 480 nucleotides at the 5'' end of 23-S RNA. By determining the sequence of 70% of this latter region, the sections which, in the presence of the protein, are resistant to RNase were localized. The region encompassing the 480 nucleotides starting at the 9th nucleotide from the 5'' end of 23-S RNA has a compact tertiary structure, which is stabilized by protein L24.