Jimpy mouse myelin revisited with freeze-fracture
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Acta Neuropathologica
- Vol. 45 (2), 129-131
- https://doi.org/10.1007/bf00691890
Abstract
Corpus callosum, cerebellum, and spinal cord from Jimpy mice, and control littermates, 15 and 21 days old, were prepared for freeze-fracture in a “cryofract” apparatus. The few myelinated axons in the Jimpy exhibited a striking paucity of particles in myelin P faces, though tight junctions were present. In addition, small maculae of particles were found on these P faces. Peripheral myelin appeared normal, both for the quantity and disposition of particles on their P faces.Keywords
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