Studies on Hypothalamic Regulation of FSH Secretion in the Androgen-Sterilized Female Rat.
- 1 June 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 110 (2), 298-300
- https://doi.org/10.3181/00379727-110-27497
Abstract
Follow-ing unilateral ovariectomy, comparable degrees of ovarian hypertrophy were observed in the normal cyclic rat (56%) and in the androgen-sterilized, persistent-estrous rat (53%). Destruction of the anterior hypothalamus of the sterile rat markedly curtailed the release of adenohypophyseal FSH. These data suggest not only that discrete FSH and LH centers exist in the hypothalamus of the rat but also that the syndrome of persistent-estrus results more likely from an imbalance in LH rather than in FSH secretion.Keywords
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