ENTEROCOLITIS COMPLICATING CHRYSOTHERAPY - CASE-REPORT AND REVIEW OF THE LITERATURE
- 1 January 1982
- journal article
- research article
- Vol. 18 (10), 1040-1043
Abstract
A case is reported of a 71-yr-old man with seronegative rheumatoid arthritis, who developed severe enterocolitis during Au therapy. Radiological studies, endoscopy and biopsies showed diffuse involvement of the stomach, duodenum and small and large intestines. The clinical course was prolonged and complicated by multiple infections. Of the 10 cases with chrysotherapy-induced enterocolitis reported in the literature, 3 were from Israel. There may be a relationship between the development of enterocolitis following Au therapy, ethnic group and HLA-B8 and DRw3 antigens.This publication has 3 references indexed in Scilit:
- HLA-DR Antigens and Toxic Reaction to Sodium Aurothiomalate and D-Penicillamine in Patients with Rheumatoid ArthritisNew England Journal of Medicine, 1980
- Complications of chrysotherapy: a review of recent studiesArchives of Internal Medicine, 1979
- Chrysotherapy. suppression of immunoglobulin synthesisArthritis & Rheumatism, 1978