An enzyme from rat liver catalysing conjugations with glutathione. 2. Replacement of nitro groups
- 1 April 1963
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 87 (1), 4-9
- https://doi.org/10.1042/bj0870004
Abstract
Rat-liver supernatant contains an enzyme that catalyses the replacement of labile aromatic nitro groups with glutathione. Evidence is presented for its identity with the enzyme that conjugates 3,4-dichloronitrobenzene and glutathione with the liberation of chloride. An explanation of the non-competitive inhibition of one second substrate by another is suggested.Keywords
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