Estimation of the Increase in Solubility of Drugs as a Function of Bile Salt Concentration
- 1 January 1996
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 13 (1), 163-167
- https://doi.org/10.1023/a:1016062224568
Abstract
Purpose. The objective of this study was to develop a model to predict the extent to which bile salts can enhance the solubility of a drug, based on the physicochemical properties of the compound....This publication has 20 references indexed in Scilit:
- Influence of bile on the gastrointestinal absorption of phenytoin in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- Determination of Partition Coefficients of Glucocorticosteroids by High-Performance Liquid ChromatographyJournal of Pharmaceutical Sciences, 1984
- Drug interactions occuring during absorption from the gastrointestinal tractPharmacology & Therapeutics, 1981
- Influence of Food on the Bioavailability of DrugsClinical Pharmacokinetics, 1978
- Solubility and Ionization Characteristics of PhenytoinJournal of Pharmaceutical Sciences, 1977
- Solubilization of hydrocortisone, dexamethasone, testosterone and progesterone by long-chain polyoxyethylene surfactantsJournal of Pharmacy and Pharmacology, 1976
- Interaction of Substituted Benzoic Acids with Polysorbate 20 MicellesJournal of Pharmaceutical Sciences, 1975
- An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometryJournal of Pharmacy and Pharmacology, 1973
- Physiologic Surface-Active Agents and Drug Absorption IV: Effect of Pre-Micellar Concentrations of Surfactant on Dissolution RateJournal of Pharmaceutical Sciences, 1969
- Human Pharmacology of Griseofulvin: The Effect of Fat Intake on Gastrointestinal Absorption11From the Department of Dermatology, University of Miami Medical School, Miami, Florida.Journal of Investigative Dermatology, 1961