Some Aspects of Pressure-Induced Equilibrium Shifts in Chromatography

Abstract

The possible advantages of pressure-induced equilibrium shifts in chromatography are explored. First, the subject of pressure-induced increases in migration rates is discussed, particularly in the light of solubility relationships already established in the high-pressure literature. Second, the more subtle equilibrium shifts leading to an enhancement of selectivity are studied. The practical implication of these equilibrium shifts are emphasized.