Metabolic Fate of S35 Administered to Rabbits as Sulfate.

Abstract
A dose of approximately 0.9 mc of S35 in the form of sodium sulfate was given orally to rabbits that were prevented from coprophagy and to rabbits treated normally. Adsorption of S35 was very rapid with the peak appearing in blood around 6 hours after dosing. Some synthesis of labeled cystine and methionine took place, with S35 labeled cystine and methionine appearing in the liver. When the habitual practice of coprophage was prevented the amount of labeled cystine and methionine in the liver was greatly reduced.