STUDY OF PENICILLIN ANTIBODIES BY FLUORESCENCE POLARIZATION AND IMMUNODIFFUSION

Abstract
1. Antibodies prepared in the rabbit to penicilloyl-rabbit serum albumin or to penicilloyl-bovine serum albumin were demonstrated by immunodiffusion and absorption methods to be apparently directed exclusively against the penicilloyl moiety. The antibodies could precipitate heavily substituted penicilloyl polylysine, as well as each other, with "reactions of identity". All could mutually deplete detectable antibodies by cross-absorption.