Tricyclic-antidepressant-induced delirium and plasma drug concentration
- 1 June 1982
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 139 (6), 822-823
- https://doi.org/10.1176/ajp.139.6.822
Abstract
Patients (14) receiving routine doses of amitriptyline developed plasma drug concentrations above 300 ng/ml. Of the 7 patients with plasma levels above 450 ng/ml, 6 developed a drug-induced delirium as opposed to none of the 7 with levels below 450 ng/ml. This adverse effect could be avoided by monitoring levels and reducing dosage when appropriate.This publication has 6 references indexed in Scilit:
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