Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription
- 1 October 2002
- journal article
- Published by Springer Nature in The EMBO Journal
- Vol. 21 (19), 5195-5205
- https://doi.org/10.1093/emboj/cdf506
Abstract
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.Keywords
This publication has 57 references indexed in Scilit:
- Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutationsNature Genetics, 2002
- Hydrocephalus, Situs Inversus, Chronic Sinusitis, and Male Infertility in DNA Polymerase λ-Deficient Mice: Possible Implication for the Pathogenesis of Immotile Cilia SyndromeMolecular and Cellular Biology, 2002
- Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnoverBiochemical Journal, 2001
- Reactive Oxygen Species-induced Phosphorylation of p53 on Serine 20 Is Mediated in Part by Polo-like Kinase-3Journal of Biological Chemistry, 2001
- Adenovirus‐mediated Transfer of p53‐related Genes Induces Apoptosis of Human Cancer CellsJapanese Journal of Cancer Research, 2000
- ATM: A mediator of multiple responses to genotoxic stressOncogene, 1999
- DNA damage activates p53 through a phosphorylation–acetylation cascadeGenes & Development, 1998
- Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathwaysNature Genetics, 1997
- Atm-Deficient Mice: A Paradigm of Ataxia TelangiectasiaCell, 1996
- p53 is required for radiation-induced apoptosis in mouse thymocytesNature, 1993