Hailey-Hailey Disease
- 1 September 1994
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 130 (9), 1143-1149
- https://doi.org/10.1001/archderm.1994.01690090067009
Abstract
Background: Chronic benign familial pemphigus (Hailey-Hailey disease) is a rare dominant genodermatosis that bothers patients by chronic recalcitrant plaques occuring mainly in the intertriginous areas. We looked for a surgical treatment that is not impaired by the complications and disadvantages of radical excision and grafting of involved areas. In 10 patients with debilitating Hailey-Hailey disease (five men, five women; age, 36 to 57 years), nine different involved areas (neck, axilla, cubital area, inframammary area, periumbilical area, groin and adjacent inner thigh, scrotum, vulva, and the perineal/perianal area) were treated by dermabrasion for a total of 46 treated regions. The plane of abrasion was located in the upper to middle dermis as verified by random sampling before and after surgery, thus documenting removal of the entire epidermis. Results: In most instances, reepithelialization was completed after 7 to 10 days followed by excellent functional and cosmetic long-term results. When examined 3 toKeywords
This publication has 20 references indexed in Scilit:
- Hailey-Hailey Disease (Familial Benign Chronic Pemphigus)Published by Springer Science and Business Media LLC ,2018
- Topical cyclosporine in chronic benign familial pemphigus (Hailey-Hailey disease)Journal of the American Academy of Dermatology, 1992
- Hailey–Hailey disease: the clinical features, response to treatment and prognosisBritish Journal of Dermatology, 1992
- Hailey-Hailey disease: a widespread abnormality of cell adhesionBritish Journal of Dermatology, 1991
- Benign familial pemphigus responsive to cyclosporine, a possible role for cellular immunity in pathogenesisBritish Journal of Dermatology, 1991
- Methotrexate for intractable benign familial chronic pemphigusBritish Journal of Dermatology, 1986
- Surgical eradication of familial benign chronic pemphigus from the axillae. Report of a caseArchives of Dermatology, 1969
- Ultraviolet-induced acantholysis in familial benign chronic pemphigus. Detection of the forme frusteArchives of Dermatology, 1967
- Experimentally Induced Acantholysis in Hailey’s benign PemphigusDermatology, 1962
- FAMILIAL BENIGN CHRONIC PEMPHIGUSArchives of Dermatology, 1939