Improved metabolic profiles in insulin-treated diabetic patients given an alpha-glucosidehydrolase inhibitor.
- 27 January 1979
- Vol. 1 (6158), 220-221
- https://doi.org/10.1136/bmj.1.6158.220
Abstract
An alpha-glucosidehydrolase inhibitor (acarbose; BAY g 5421) taken with food was compared with dummy tablets in seven insulin-treated diabetic patients over eight-hour periods that included breakfast, lunch, and two snacks. Acarbose diminished the postprandial increases in blood glucose, lactate, and pyruvate concentrations and may therefore be of value in the management of insulin-dependent diabetes.Keywords
This publication has 5 references indexed in Scilit:
- SUCROSE MALABSORPTION IN MAN AFTER INGESTION OF α-GLUCOSIDEHYDROLASE INHIBITORThe Lancet, 1978
- Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity.BMJ, 1978
- ?-Glucosidase inhibitorsThe Science of Nature, 1977
- DIABETES-MELLITUS AND ITS DEGENERATIVE COMPLICATIONS - A PROSPECTIVE-STUDY OF 4,400 PATIENTS OBSERVED BETWEEN 1947 AND 19731977
- UNABSORBABLE CARBOHYDRATES AND DIABETES: DECREASED POST-PRANDIAL HYPERGLYCÆMIAThe Lancet, 1976