An epidemiological investigation of Norwalk virus infection in South Africa
- 1 April 1996
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 116 (2), 203-206
- https://doi.org/10.1017/s0950268800052444
Abstract
SUMMARY A study was carried out to determine the incidence and seroprevalence of Norwalk virus (NV) in the Pretoria area, South Africa, using a recombinant NV (rNV) immunoassay for the detection of serum IgG antibodies. Maternal antibody was detectable in infants' sera up to approximately 6 months of age. Infection with NV was detected serologically in the second year of life and the seroprevalence of NV IgG rose from 37·1% at 7–11 months of age to 62·1% by the age of 40 years. No significant differences in seroprevalence of NV IgG antibody was evident between subjects of European or African ethnic origin, where overall seroprevalence rates were 56·4% and 53·9% respectively.Keywords
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