Histopathology of Amino Acid Deficiencies. II. Threonine.

Abstract

Young male rats fed a “synthetic” diet, complete in every respect except for the total lack of threonine, showed marked loss in weight, interruption of somatic growth, atrophy of the testes and accessory structures and alterations in the chromophilic cells of the anterior pituitary. The deficiency effects were reversed by adding the missing amino acid to the diet.