THE RAPID PREPARATION OF SYNAPTOSOMES, USING A VERTICAL ROTOR

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  • 1 January 1981
    • journal article
    • research article
    • Vol. 37 (3), 795-797
Abstract
A rapid method for the preparation of isolated [rat] nerve terminals (synaptosomes) is described. The material, prepared using a vertical rotor, is compared biochemically with material prepared by conventional techniques. The synaptosomes possess many characteristics expected of isolated nerve terminals, including noradrenaline [norepinephrine] release and transport against a concentration gradient.