Effect of Cortisone Acetate on an Experimental Purulent Infectious Arthritis of White Mice

Abstract

The response in mice to infection with various doses of strain JST of alpha type streptococcus is highly uniform when measured in terms of mortality plus incidence of arthritis. 5-7 days of treatment with cortisone acetate in doses of 0.015 g./kg. and above produce statistically significant increases in incidence of mortality plus arthritis produced by this organism in mice.