Effect of Irradiation and Chemotherapeutic Agents on the Capillaries of Ehrlich Ascites Carcinoma of Mice

Abstract
The effect of irradiation and chemotherapeutic agents [5-fluorouracil, bleomycin] on the capillaries of experimental solid tumors [mouse Ehrlich ascites carcinoma cells] was analyzed by the resin cast method. The most evident change of the 5 vascular layers was rarefaction of the newly produced extruding capillaries on the surface of the tumor mass, which was related to the tumor growth.