Distemper and multiple sclerosis in Sitka, Alaska

Abstract
The annual incidence of multiple sclerosis (MS) in Sitka, Alaska, was determined in the period 1949–1979, spanning a severe 1965 epidemic of canine distemper in the dog population. Three patients were identified, and each had the onset of MS in 1969 or 1970. This time cluster of MS is significant (p < 0.01) and was predicted by the hypothesis that MS may be linked to canine distemper virus.