A receptor for the third component of complement in the human renal glomerulus
Open Access
- 1 October 1975
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 142 (4), 1029-1034
- https://doi.org/10.1084/jem.142.4.1029
Abstract
In the course of studying the nature of mononuclear cellular infiltrates in tissue sections of human kidney it was noted that indicator sheep erythrocytes densely coated with the third component of complement (C3) specifically adhered to all of the glomeruli in the tissue sections. The deposition of complement (C) within the glomerulus is a feature of many immunologically related renal diseases (1,2), yet the precise mechanism by which C is deposited remains unexplained. We feel that this observation, suggesting the presence of a receptor for C, is, therefore, of particular interest.This publication has 7 references indexed in Scilit:
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