Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
- 1 December 1999
- journal article
- Published by Elsevier in Molecular and Cellular Neuroscience
- Vol. 14 (6), 419-427
- https://doi.org/10.1006/mcne.1999.0811
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Metalloprotease MP100: a synaptic protease in rat brainBrain Research, 1999
- Processing of the Alzheimer's Disease Amyloid Precursor Protein inPichia pastoris: Immunodetection of α-, β-, and γ-Secretase ProductsBiochemistry, 1998
- Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cellsNature Medicine, 1997
- Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptidesNature Medicine, 1997
- Cathepsin D displays in vitro β-secretase-like specificityBrain Research, 1997
- Analysis of Heterogeneous βA4 Peptides in Human Cerebrospinal Fluid and Blood by a Newly Developed Sensitive Western Blot AssayJournal of Biological Chemistry, 1996
- The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathwayNature Medicine, 1995
- The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cellsBiochemical Journal, 1993
- Putative N‐terminal splitting enzyme of amyloid A4 peptides is the multicatalytic proteinase, ingensin, which is widely distributed in mammalian cellsFEBS Letters, 1989
- Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinBiochemical and Biophysical Research Communications, 1984