Adenovirus Dodecahedron Allows Large Multimeric Protein Transduction in Human Cells
Open Access
- 15 April 2003
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 77 (8), 4960-4964
- https://doi.org/10.1128/jvi.77.8.4960-4964.2003
Abstract
Adenovirus dodecahedron is a virus-like particle composed of only two viral proteins of human adenovirus serotype 3 that are responsible for virus attachment and internalization. We show here that this dodecameric particle, devoid of genetic information, efficiently penetrates human cells and can deliver large multimeric proteins such as immunoglobulins.Keywords
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