Generation of b-wave currents in the skate retina.
- 1 November 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (11), 5727-5731
- https://doi.org/10.1073/pnas.75.11.5727
Abstract
Pk kinetics within the skate [Raja erinacea or R. ocellata] retina were monitored extracellularly with K+-selective electrodes. Two sources of K+ efflux were detected in response to photic stimulation: one in the distal retina in the region of the outer plexiform layer, and the other at a more proximal location near the border between the inner nuclear and inner plexiform layers. The magnitude of the K+ efflux at these retinal depths was affected differently by spot and full-field illumination, suggesting that the 2 sources originate from different classes of neuron. Both sources may be associated with current sinks provided by the Mueller cells, thereby establishing radial current paths along the lengths of these elements. A model was proposed in which asymmetries in the magnitudes of these currents gave rise to the b-wave of the electroretinogram. Extracellular field potentials recorded differentially at various retinal depths, and in response to changes in stimulus configuration, were consistent with predictions of the model.This publication has 10 references indexed in Scilit:
- Potassium efflux in heart muscle during activity: extracellular accumulation and its implications.The Journal of Physiology, 1978
- Light-evoked changes in extracellular potassium concentration in mudpuppy retinaBrain Research, 1978
- Relationship between Muller cell responses, a local transretinal potential, and potassium fluxJournal of Neurophysiology, 1977
- Correlation of light-induced changes in retinal extracellular potassium concentration with c-wave of the electroretinogramJournal of Neurophysiology, 1976
- Potassium efflux and accumulation in heart muscle. Evidence from K +/- electrode experimentsBiophysical Journal, 1976
- Rapid Changes of Potassium Concentration at the Outer Surface of Exposed Single Neurons during Membrane Current FlowThe Journal of general physiology, 1973
- S-Potentials in the Skate RetinaThe Journal of general physiology, 1971
- Visual Adaptation in the Retina of the SkateThe Journal of general physiology, 1970
- Intracellular responses of the Müller (glial) cells of mudpuppy retina: their relation to b-wave of the electroretinogram.Journal of Neurophysiology, 1970
- Some properties of components of the cat electroretinogram revealed by local recording under oilThe Journal of Physiology, 1965