The effects of astemizole on histamine-induced weal and flare
- 1 January 1983
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Pharmacology
- Vol. 25 (4), 547-551
- https://doi.org/10.1007/bf00542126
Abstract
The effect of astemizole on the weal and flare response to intradermal histamine has been studied in normal volunteers after single dosing, and in patients with urticaria and pruritus after chronic dosing with the drug. Single doses of astemizole (40 mg) in normal volunteers significantly reduced histamine weal and flare at 24 and 48 h (pppppp1 antagonist activity.Keywords
This publication has 3 references indexed in Scilit:
- Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine.British Journal of Clinical Pharmacology, 1982
- HISTAMINE WEAL FORMATION AND ABSORPTION IN MANBritish Journal of Pharmacology, 1980
- Inhibitory activity of terfenadine on histamine-induced skin wheals in manEuropean Journal of Clinical Pharmacology, 1977