Nonhistone Chromosomal Protein Synthesis: Utilization of Preexisting and Newly Transcribed Messenger RNA's
- 6 July 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 181 (4094), 71-73
- https://doi.org/10.1126/science.181.4094.71
Abstract
Treatment of HeLa S3 cells with actinomycin D during mitosis suppresses the synthesis of several major classes of nonhistone chromosomal proteins during the subsequent period before DNA replication, but allows the synthesis of other species of these proteins. Such results are consistent with the utilization of preexisting, as well as newly transcribed, messenger RNA's for nonhistone chromosomal protein synthesis during the prereplicative phase of the cell cycle.Keywords
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