Inhibition of Established Tuberculin Hypersensitivity by Methptrexate,

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Abstract
Summary Actively or passively established tuberculin hypersensitivity in Strain 2 guinea pigs is suppressed by methotrexate treatment for as short a period as 15 days. The suppression of this immune response does not seem to be due to a lymphopenic or anti-inflammatory effect of the drug.

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