Polyribosomes: Size in Normal and Polio-Infected HeLa Cells
- 27 December 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3600), 1658-1663
- https://doi.org/10.1126/science.142.3600.1658
Abstract
HeLa cells normally contain a distribution of polysome sizes, and the largest polysomes contain over 40 ribosomes. After infection with polio virus and actinomycin-D treatment, a new class of polio-induced polysomes are found, some of which contain up to 60 ribosomes. Examinaton of these polysomes suggests a mechanism for protein synthesis with this polycistronic RNA.Keywords
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