Alkaloid, Lignan and Flavonoid Constituents ofHaplophyllum tuberculatumfrom Sudan

Abstract

The aerial parts of Haplophyllum tuberculatum collected in Sudan have yielded the furoquinoline alkaloid skimmianine, the lignan justicidin-A, and 5,7,4′-trihydroxy-6-methoxy-3-O-glucosyl flavone. Skimmianine was identified by direct comparison with authentic material; justicidin-A by analysis of spectral data and by examination of lanthanide induced shifts in the PMR spectrum; and 5,7,4′-trihydroxy-6-methoxy-3-O-glucosyl flavone by spectral analysis of the original isolate and of its hydrolysis product.