Glycosaminoglycans of Rat Cerebellum: II. A Developmental Study
- 1 March 1985
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 44 (3), 907-910
- https://doi.org/10.1111/j.1471-4159.1985.tb12902.x
Abstract
Total and individual glycosaminoglycans (GAGs) were determined in rat cerebellum in tissue explants at various postnatal ages. The major constituents of GAGs were chondroitin sulfate (CS), hyaluronic acid (HA), and heparan sulfate (HS). Dermatan sulfate (DS) and keratan sulfate (KS) could not be detected and therefore each amounts to 3H]glucosamine into individual GAGs was highest for HS at postnatal day 6, whereas HA showed intermediate and CS the lowest levels of incorporation during the first postnatal week. All major GAGs showed the lowest incorporation values at adult ages.Keywords
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