Serological Typing of Ureaplasma urealyticum Isolates from Urethritis Patients by an Agar Growth Inhibition Method
- 31 October 1978
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 8 (5), 566-574
- https://doi.org/10.1128/jcm.8.5.566-574.1978
Abstract
An agar growth inhibition method for serotyping U. urealyticum is described and the results of applying this method to serotyping 338 strains of the organism are presented. The serotyped strains consisted of cloned isolates from male patients with primary and recurrent nongonococcal urethritis (NGU), isolates from symptomatic patients with other genitourinary tract infections and disorders and isolates from asymptomatic carriers of U. urealyticum in the genitourinary tract (controls). Among 122 male patients with NGU, serotype 4 was associated most frequently (52%) with this disease at Camp Lejeune, N.C. [North Carolina, USA]. Seventeen percent of the isolates were type 2. The remaining isolates consisted of types 1, 3, 6 and 8 and accounted for 6-9% each of the serotypes isolated from the NGU group. Types 5 and 7 were not isolated. Among 91 symptomatic patients with other genitourinary tract infections and disorders, U. urealyticum type 4 also was associated most frequently (37%) with these disorders. The remaining isolates, represented by types 1, 2, 3, 6, 7 and 8, accounted for 9-15% each of the types isolated from this group. Type 5 was not isolated. Among 125 symptom-free carriers of U. urealyticum in the genitourinary tract, type 8 was recovered most frequently (30%), whereas type 4 was isolated next most frequently (24%). The remaining isolates consisted of types 1, 2, 3, 5 and 6 and accounted for 2-15% each in this asymptomatic control group. Type 7 was not isolated. Of the present 8 serotypes of U. urealyticum studied in this investigation, type 4 was associated most frequently with disease (NGU) and certain other disorders of the genitourinary tract at Camp Lejeune. A previously unknown association of U. urealyticum with frequently abacteriuric, unexplained pyuria (with or without urethral pruritis and dysuria) is reported, suggesting the existence of asymptomatic Ureaplasma urethritis.This publication has 24 references indexed in Scilit:
- Comparison of growth inhibition and immunofluorescence tests in serotyping clinical isolates of Ureaplasma urealyticum.Sexually Transmitted Infections, 1977
- The Etiology of Nongonococcal Urethritis in Men Attending a Venereal Disease ClinicSexually Transmitted Diseases, 1977
- Distribution of eight serotypes of Ureaplasma urealyticum in cases of non-gonococcal urethritis and of gonorrhoea, and in healthy persons.Sexually Transmitted Infections, 1976
- APPLICATION OF INDIRECT IMMUNOFLUORESCENCE, INDIRECT HAEMAGGLUTINATION AND POLYACRYLAMIDE‐GEL ELECTROPHORESIS TO HUMAN T‐MYCOPLASMASActa Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology, 1974
- Differential Methods for Identification of T-Mycoplasmas Based on Demonstration of UreaseThe Journal of Infectious Diseases, 1973
- Urease color test medium U-9 for the detection and identification of "T" mycoplasms in clinical material.1970
- IDENTIFICATION OF “T” MYCOPLASMAS IN PRIMARY AGAR CULTURES BY MEANS OF A DIRECT TEST FOR UREASE*Annals of the New York Academy of Sciences, 1970
- Immune Inactivation of T-Strain MycoplasmasThe Journal of Infectious Diseases, 1970
- Strain of Mycoplasma Associated with Human Reproductive FailureScience, 1967
- RELATIONSHIPS BETWEEN MYCOPLASMA AND THE ETIOLOGY OF NONGONOCOCCAL URETHRITIS AND REITER'S SYNDROME*Annals of the New York Academy of Sciences, 1967