A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
- 1 July 1990
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 346 (6281), 245-250
- https://doi.org/10.1038/346245a0
Abstract
A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.Keywords
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